INCREASED CSF NEOPTERIN LEVELS IN SUBARACHNOID HEMORRHAGE

被引：21

作者：

MATHIESEN, T ^{[1
]}

FUCHS, D ^{[1
]}

WACHTER, H ^{[1
]}

VONHOLST, H ^{[1
]}

机构：

[1] UNIV INNSBRUCK,INST MED CHEM & BIOCHEM,A-6020 INNSBRUCK,AUSTRIA

来源：

JOURNAL OF NEUROSURGERY | 1990年 / 73卷 / 01期

关键词：

Cerebrospinal fluid; Ischemia; Neopterin; Serum; Subarachnoid hemorrhage; T cell activation;

D O I：

10.3171/jns.1990.73.1.0069

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neopterin concentrations, reflecting T-cell macrophage activation, were analyzed in serum and cerebrospinal fluid (CSF) obtained from 14 patients with subarachnoid hemorrhage (SAH). Neopterin concentrations were evaluated in both the serum and CSF. The increase in neopterin concentrations was most marked in the CSF, rising from Days 1 to 3 through Days 6 to 9; levels were highest in patient suffering from delayed cerebral ischemia. The present data were interpreted as signs of an ongoing T cell activation both systematically and in the CSF compartment following SAH.

引用

页码：69 / 71

页数：3

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