THE STUDY OF AGGLUTINATION OF TRYPSIN-TREATED SHEEP RED-CELLS BY CORYNEBACTERIUM-DIPHTHERIAE STRAINS

被引：2

作者：

KOSTYUKOVA, NN ^{[1
]}

KARAS, SR ^{[1
]}

KACIMOVA, DY ^{[1
]}

机构：

[1] BAKU EPIDEMIOL HYG & OCCUPAT DIS RES INST, BAKU, AZERBAIJAN, USSR

来源：

FEMS MICROBIOLOGY IMMUNOLOGY | 1992年 / 89卷 / 04期

关键词：

DIPHTHERIA; CORYNEBACTERIUM-DIPHTHERIAE; ADHESIN; COLONIZATION; PATHOGENIC FACTOR;

D O I：

10.1016/0378-1097(92)90121-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

620 Corynebacterium diphtheriae strains from 472 sick and healthy persons were studied for their adhesive activity (AA) in direct agglutination of trypsin-treated sheep erythrocytes. Toxigenic strains had more active AA than non-toxigenic ones which was not dependent on the presence of toxin in the culture. Neither biotype nor serotype of the strains correlated with their AA. Several lysotypes among toxigenic and non-toxigenic strains were more active than others. Toxigenic strains from patients had higher AA than those from carriers. Both toxigenic and non-toxigenic strains isolated from the prolonged carriers possessed the highest AA. It was concluded that AA measured in this way was an important colonization factor for all diphtheria strains and a pathogenicity factor for toxigenic strains.

引用

页码：231 / 234

页数：4

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