EFFECT OF CALCIUM ON THE ZINC UPTAKE BY BRUSH-BORDER MEMBRANE-VESICLES ISOLATED FROM THE RAT SMALL-INTESTINE

被引：15

作者：

GUNSHIN, H ^{[1
]}

NOGUCHI, T ^{[1
]}

NAITO, H ^{[1
]}

机构：

[1] UNIV RYUKYUS,SCH MED,DEPT PREVENT MED,OKINAWA 90301,JAPAN

来源：

AGRICULTURAL AND BIOLOGICAL CHEMISTRY | 1991年 / 55卷 / 11期

关键词：

D O I：

10.1080/00021369.1991.10857152

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

To assess the nutritional defects of some trace elements caused by an excess supplementation of calcium, an in vitro study was undertaken on brush border membrane vesicles (BBMV) isolated from the small intestinal mucosa of normal rats. The uptake of Zn-65(2+) tended to be saturable with increasing concentration of Zn2+, which was decreased by adding an excess concentration of IIa cations or of Mn2+. The degree of inhibition was inversely proportional to the ionic radius of these divalent cations, except for manganese. All of these inhibition processes proceeded without change in the maximum velocity of Zn2+ uptake, indicating the intervention by a common carrier for these cations during the course of mucosal uptake.

引用

页码：2813 / 2816

页数：4

共 18 条

[1] THE SEQUENTIAL ENZYMATIC DETERMINATION OF DNA AND RNA [J].

BENTLE, LA ;

DUTTA, S ;

METCOFF, J .

ANALYTICAL BIOCHEMISTRY, 1981, 116 (01) :5-16

[2] EFFECT OF CALCIUM AND PHOSPHORUS SALTS ON THE UTILIZATION OF IRON BY ANAEMIC RATS [J].

CHAPMAN, DG ;

CAMPBELL, JA .

BRITISH JOURNAL OF NUTRITION, 1957, 11 (02) :127-133

[3]

DICK A. T., 1954, AUSTRALIAN VET JOUR, V30, P196, DOI 10.1111/j.1751-0813.1954.tb08199.x

[4] DIFFERENTIAL ISOLATION OF MICROVILLOUS AND BASOLATERAL PLASMA-MEMBRANES FROM INTESTINAL-MUCOSA - MUTUALLY EXCLUSIVE DISTRIBUTION OF DIGESTIVE ENZYMES AND OUABAIN-SENSITIVE ATPASE [J].

FUJITA, M ;

KAWAI, K ;

OHTA, H ;

NAKAO, M ;

MATSUI, H .

BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 274 (02) :336-&

[5] TRACE-ELEMENTS IN HUMAN-MILK, COWS MILK, AND INFANT FORMULA [J].

GUNSHIN, H ;

YOSHIKAWA, M ;

DOUDOU, T ;

KATO, N .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1985, 49 (01) :21-26

[6]

GUNSHIN H, 1988, NUTR REP INT, V37, P1021

[7]

GUNSHIN H, 1989, Annals of Physiological Anthropology, V8, P227

[8] INHIBITION OF INTESTINAL CALCIUM-UPTAKE BY CADMIUM AND EFFECT OF A LOW CALCIUM DIET ON CADMIUM RETENTION [J].

HAMILTON, DL ;

SMITH, MW .

ENVIRONMENTAL RESEARCH, 1978, 15 (02) :175-184

[9] ZINC-65 ABSORPTION AND TURNOVER IN RATS .I. A PROCEDURE TO DETERMINE ZINC-65 ABSORPTION AND ANTAGONISTIC EFFECT OF CALCIUM IN A PRACTICAL DIET [J].

HETH, DA ;

HOEKSTRA, WG .

JOURNAL OF NUTRITION, 1965, 85 (04) :367-&

[10] ROLE OF ALKALINE-PHOSPHATASE IN PHOSPHATE-UPTAKE INTO BRUSH-BORDER MEMBRANE-VESICLES FROM HUMAN INTESTINAL-MUCOSA [J].

HIRANO, K ;

IIIZUMI, Y ;

MORI, Y ;

TOYOSHI, K ;

SUGIURA, M ;

IINO, S .

JOURNAL OF BIOCHEMISTRY, 1985, 97 (05) :1461-1466

← 1 2 →