1ST AL-26 ANALYSES AT THE ANTARES-AMS-CENTER - UPTAKE VIA ORAL INGESTION OF AL-26 IN RATS

被引：18

作者：

FINK, D

WALTON, J

HOTCHKIS, MAC

JACOBSEN, GE

LAWSON, EM

SMITH, AM

TUNIZ, C

WILCOX, D

机构：

[1] AUSTRALIAN INST BIOMED RES LTD, BONDI JNCT, NSW 2022, AUSTRALIA

[2] SYDNEY WATER BOARD, SYDNEY, NSW 2000, AUSTRALIA

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 1994年 / 92卷 / 1-4期

关键词：

D O I：

10.1016/0168-583X(94)96057-7

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

As the debate on the role played by aluminium in Alzheimer's disease remains a controversial one, the mechanism and degree of uptake of aluminium into brain tissue is not well understood nor quantified. We report here results from the initial phase of our study of aluminium uptake and retention in tissues of rats following oral administration of a tracer dose of Al-26. An account Of OUT biomedical findings in old rats will be described elsewhere. For a young rat population, we find Al-26 retention in the liver to be 7 times that in the brain. A description of our experience in performing aluminium measurements of biological tissues is described and interpretation of the findings are given.

引用

页码：473 / 477

页数：5

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