THE EFFECT OF APHIDICOLIN ON DNA-REPAIR IN RESTING AND MITOGEN STIMULATED HUMAN-LYMPHOCYTES

被引：6

作者：

BOHR, V ^{[1
]}

KOBER, L ^{[1
]}

机构：

[1] PANUM INST, DEPT BIOCHEM, BLEGDAMSVEJ 3C, DK-2200 COPENHAGEN, DENMARK

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1982年 / 108卷 / 02期

关键词：

D O I：

10.1016/0006-291X(82)90899-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aphidicolin inhibits DNA repair in human lymphocytes as measured by unscheduled DNA synthesis and the rejoining of strand breaks. When the lymphocytes are mitogen-stimulated, sensitivity of DNA repair towards aphidicolin decreases, possibly due to the induction of the .beta. DNA polymerase .beta.

引用

页码：797 / 803

页数：7

共 12 条

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