INFLUENCE OF VESSEL DIAMETER ON RED-CELL DISTRIBUTION AT MICROVASCULAR BIFURCATIONS

被引:25
作者
CARR, RT
WICKHAM, LL
机构
[1] Department of Chemical Engineering, University of New Hampshire, Durham
关键词
D O I
10.1016/0026-2862(91)90020-C
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
The uneven distribution of red blood cells (RBCs) to daughter branches at microvascular bifurcations, often referred to as "plasma skimming," has been characterized in previous studies by comparisons of flux-flow plots of red cell flow fraction (F*) versus volumetric flow fraction (Q*) at single junctions. Comparisons of flux-flow plots for single bifurcations with differing daughter/parent vessel diameter ratios ( Dd Dp = 1.0 vs 0.5) have been made to reveal the influence of vessel size on red cell distribution at vessel junctions of four different geometries (100 × 100, 50 × 50, 100 × 50, 50 × 25 μm). Experimental data determined by effluent collection were compared to those from video fluorescence microscopy experiments, as well as to numerical computations from theoretical models. Statistical comparisons using a likelihood ratio test indicate that vessel diameter ratio, Dd Dp has no detectable influence on RBC distribution in these microvascular bifurcations. © 1991.
引用
收藏
页码:184 / 196
页数:13
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