DETECTION OF GENOMIC SEQUENCES OF RESPIRATORY SYNCYTIAL VIRUS IN OTITIS-MEDIA WITH EFFUSION IN CHILDREN

被引：21

作者：

OKAMOTO, Y ^{[1
]}

SHIROTORI, K ^{[1
]}

TOGAWA, K ^{[1
]}

NAKAZAWA, M ^{[1
]}

PATEL, JA ^{[1
]}

KUDO, K ^{[1
]}

ITO, E ^{[1
]}

OGRA, PL ^{[1
]}

机构：

[1] UNIV TEXAS,MED BRANCH,CHILDRENS HOSP,DEPT PEDIAT,GALVESTON,TX 77550

来源：

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | 1992年 / 101卷 / 10期

关键词：

OTITIS MEDIA WITH EFFUSION; POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS;

D O I：

10.1177/0003489492101S1003

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The reverse transcriptase-polymerase chain reaction and the nested polymerase chain reaction were used for detection of respiratory syncytial virus (RSV) sequences in middle ear effusions collected from children with otitis media. Sequences of RSV were detected in 21 of 34 samples tested. These samples were collected during and/or after natural outbreaks of RSV infection in the community. In those patients from whose nasopharynges RSV was isolated, the viral sequences were highly detectable (75%) in the effusions. These observations suggest RSV as an important factor in the pathogenesis of otitis media with effusion.

引用

页码：7 / 10

页数：4

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