HYPOTHYROIDISM IN INFANTS WITH NEPHROTIC SYNDROME

被引：26

作者：

MATTOO, TK

机构：

[1] Paediatric Renal Service, King Fahad National Guard Hospital, Riyadh

来源：

PEDIATRIC NEPHROLOGY | 1994年 / 8卷 / 06期

关键词：

NEPHROTIC SYNDROME; HYPOTHYROIDISM;

D O I：

10.1007/BF00869078

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Thyroid function indices were studied in five children with nephrotic syndrome in the Ist year of life. Four had primary hypothyroidism as defined by low serum free tri-iodothyronine (FT3) and free thyroxine (FT4), and high serum thyroid-stimulating hormone (TSH) levels. One patient with low serum FT3 and FT4 had a normal TSH level, T-4 replacement therapy lowered TSH to normal levels in all four patients and normalized FT4 in three of them, There were no significant changes in serum FT3 levels. Adrenal function was studied in three patients, none had adrenal calcification or hypoadrenocorticism. This study supports the existence of a hypothyroid state in some infants with nephrotic syndrome, Routine thyroid screening and early replacement therapy is recommended.

引用

页码：657 / 659

页数：3

共 11 条

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