PHARMACOLOGICAL CHARACTERIZATION OF TARDIVE AKATHISIA

被引：29

作者：

SACHDEV, P ^{[1
]}

CHEE, KY ^{[1
]}

机构：

[1] PRINCE HENRY HOSP,INST NEUROPSYCHIAT,LITTLE BAY,NSW 2036,AUSTRALIA

来源：

BIOLOGICAL PSYCHIATRY | 1990年 / 28卷 / 09期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0006-3223(90)90515-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A patient with tardive neuroleptic-induced akathisia was investigated with multiple pharmacological challenges. It was noted that the patient responded positively to benztropine, bromocriptine, and propranolol, and negatively to physostigmine, and showed little or no response to discontinuation of neuroleptics and challenges with metoclopramide, metoprolol, atenoiol, and clonidine. The implications of this pharmacological characterization for the understanding of the pathophysiology of tardive akathisia in relation to acute akathisia and tardive dyskinesia are discussed. © 1990.

引用

页码：809 / 818

页数：10

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