CIRCADIAN RHYTHM OF PLASMA 11-HYDROXYCORTICOSTEROIDS IN PSYCHIATRIC DISORDERS

被引：15

作者：

CONROY, RTW

HUGHES, BD

MILLS, JN

机构：

[1] Department of Physiology, University of Manchester

[2] Parkside Hospital, Macclesfield

来源：

BRITISH MEDICAL JOURNAL | 1968年 / 3卷 / 5615期

关键词：

D O I：

10.1136/bmj.3.5615.405

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Studies of the circadian rhythm in plasma 11-O.H.C.S. levels showed that a subgroup of affective psychodcs had higher plasma 11-OHCS values as compared with schizophrenic and other psychotic subgroups, and a somewhat less regular rhythm. One patient with depression who was studied over 48-hour periods showed a reduction in plasma 11-OHCS levels with clinical recovery. An accentuated fall and rise in plasma 11-OHCS values in the night and early morning samples, respectively, was observed in the schizophrenic subgroup. © 1968, British Medical Journal Publishing Group. All rights reserved.

引用

收藏

页码：405 / &

相关论文

共 28 条

[1] THE NORMAL LEVELS OF 17-HYDROXYCORTICOSTEROIDS IN THE PERIPHERAL BLOOD OF MAN [J].

BLISS, EL ;

SANDBERG, AA ;

NELSON, DH ;

EIKNES, K .

JOURNAL OF CLINICAL INVESTIGATION, 1953, 32 (09) :818-823

[2] STUDIES OF SLEEP DEPRIVATION - RELATIONSHIP TO SCHIZOPHRENIA [J].

BLISS, EL ;

CLARK, LD ;

WEST, CD .

ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1959, 81 (03) :348-359

[3] PSYCHOLOGICAL STRESS AND ENDOCRINE FUNCTIONS - BLOOD-LEVELS OF ADRENOCORTICAL AND THYROID-HORMONES IN ACUTELY DISTURBED PATIENTS [J].

BOARD, F ;

PERSKY, H ;

HAMBURG, DA .

PSYCHOSOMATIC MEDICINE, 1956, 18 (04) :324-333

[4] DEPRESSIVE AFFECT AND ENDOCRINE FUNCTIONS - BLOOD LEVELS OF ADRENAL CORTEX AND THYROID HORMONES IN PATIENTS SUFFERING FROM DEPRESSIVE REACTIONS [J].

BOARD, F ;

WADESON, R ;

PERSKY, H .

ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1957, 78 (DEC) :612-620

[5] DIURNAL RHYTHM OF PLASMA CORTISOL CONCENTRATION IN DEPRESSION [J].

BRIDGES, PK ;

JONES, MT .

BRITISH JOURNAL OF PSYCHIATRY, 1966, 112 (493) :1257-&

[6] PLASMA 11-HYDROXYCORTICOSTEROIDS IN AFFECTIVE DISORDERS [J].

BROOKSBANK, BW ;

COPPEN, A .

BRITISH JOURNAL OF PSYCHIATRY, 1967, 113 (497) :395-+

[7]

BUSH I, 1954, RECENT PROGR HORMONE, V9, P449

[8]

CONROY RTW, 1968, J PHYSIOL-LONDON, V196, pP129

[9]

DOIG RJ, 1966, BRIT J PSYCHIAT, V112, P1263, DOI 10.1192/bjp.112.493.1263

[10] DETERMINATION OF 17,21-HYDROXYCORTICOSTEROIDS IN PLASMA [J].

EIKNES, K ;

NELSON, DH ;

SAMUELS, LT .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1953, 13 (10) :1280-1282