NEUROPSYCHOLOGICAL DEFICITS IN ABSTINENT COCAINE ABUSERS - PRELIMINARY FINDINGS AFTER 2 WEEKS OF ABSTINENCE

被引：117

作者：

BERRY, J ^{[1
]}

VANGORP, WG ^{[1
]}

HERZBERG, DS ^{[1
]}

HINKIN, C ^{[1
]}

BOONE, K ^{[1
]}

STEINMAN, L ^{[1
]}

WILKINS, JN ^{[1
]}

机构：

[1] W LOS ANGELES VA MED CTR,DIV BRENTWOOD,ALCOHOL & DRUG TREATMENT PROGRAM,11301 WILSHIRE BLVD,LOS ANGELES,CA 90073

来源：

DRUG AND ALCOHOL DEPENDENCE | 1993年 / 32卷 / 03期

关键词：

NEUROPSYCHOLOGY; COCAINE ABUSE; COGNITION;

D O I：

10.1016/0376-8716(93)90087-7

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Sixteen subjects hospitalized for treatment of cocaine dependence were administered a battery of neuropsychological tests within 72 h of last cocaine use and again approximately 2 weeks later. Twenty-one non-cocaine using control subjects, matched for age, gender, ethnicity and education, also received neuropsychological testing. Abstinence from mood altering substances during the 2-week study period was verified for both groups on three occasions using quantitative urine analysis. The results suggest that recent cocaine use is associated with impairment in memory, visuospatial abilities, and concentration during the acute phase of withdrawal, independent of withdrawal-related depression. Furthermore, many of these deficits appear to persist at least 2 weeks beyond cessation of cocaine use.

引用

页码：231 / 237

页数：7

共 20 条

[1] NEUROPSYCHOLOGICAL DEFICITS IN CHRONIC COCAINE ABUSERS [J].