SUPERCOILING, KNOTTING, LOOPING AND OTHER LARGE-SCALE CONFORMATIONAL PROPERTIES OF DNA

被引：13

作者：

VOLOGODSKII, AV

COZZARELLI, NR

机构：

[1] Department of Molecular and Cell Biology, University of California, Berkeley

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1994年 / 4卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-440X(94)90105-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The large-scale conformational properties of DNA are important for its function. This review covers new insights into DNA supercoiling and the first investigations of knot formation during the random cyclization of DNA. The studies of knotting showed that DNA conformational properties can depend strongly on ionic conditions. We discuss the utility of the worm-like chain model for the description of DNA conformations.

引用

收藏

页码：372 / 375

页数：4

相关论文

共 31 条

[1]

BATES A, 1993, DNA TOPOLOGY

[2] TWIST AND WRITHE OF A DNA LOOP CONTAINING INTRINSIC BENDS [J].

BAUER, WR ;

LUND, RA ;

WHITE, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (03) :833-837

[3] THE TWIST, WRITHE AND OVERALL SHAPE OF SUPERCOILED DNA CHANGE DURING COUNTERION-INDUCED TRANSITION FROM A LOOSELY TO A TIGHTLY INTERWOUND SUPERHELIX - POSSIBLE IMPLICATIONS FOR DNA-STRUCTURE IN-VIVO [J].

BEDNAR, J ;

FURRER, P ;

STASIAK, A ;

DUBOCHET, J ;

EGELMAN, EH ;

BATES, AD .

JOURNAL OF MOLECULAR BIOLOGY, 1994, 235 (03) :825-847

[4] CONDENSATION OF DNA BY MULTIVALENT CATIONS - CONSIDERATIONS ON MECHANISM [J].

BLOOMFIELD, VA .

BIOPOLYMERS, 1991, 31 (13) :1471-1481

[5] THERMODYNAMICS AND EQUILIBRIUM SEDIMENTATION ANALYSIS OF THE CLOSE APPROACH OF DNA-MOLECULES AND A MOLECULAR ORDERING TRANSITION [J].

BRIAN, AA ;

FRISCH, HL ;

LERMAN, LS .

BIOPOLYMERS, 1981, 20 (06) :1305-1328

[6] KINETICS OF DNA SUPERCOILING STUDIED BY BROWNIAN DYNAMICS SIMULATION [J].

CHIRICO, G ;

LANGOWSKI, J .

BIOPOLYMERS, 1994, 34 (03) :415-433

[7] LIGHT-SCATTERING OF DNA PLASMIDS CONTAINING REPEATED CURVED INSERTIONS - ANOMALOUS COMPACTION [J].

CHIRICO, G ;

BERETTA, S ;

BALDINI, G .

BIOPHYSICAL CHEMISTRY, 1992, 45 (02) :101-108

[8]

DUBOCHET J, 1992, METHOD ENZYMOL, V211, P507

[9]

FENLEY MO, 1994, IN PRESS BIOPOLYMERS

[10] ELECTRICAL DOUBLE-LAYER FORCES - A MONTE-CARLO STUDY [J].

GULDBRAND, L ;

JONSSON, B ;

WENNERSTROM, H ;

LINSE, P .

JOURNAL OF CHEMICAL PHYSICS, 1984, 80 (05) :2221-2228

← 1 2 3 4 →