A SHORT ENANTIOSELECTIVE ROUTE TO CORYNANTHE ALKALOID PRECURSORS

被引：28

作者：

LEONARD, J

OUALI, D

RAHMAN, SK

机构：

[1] Department of Chemistry, Applied Chemistry University of Salford, Salford

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)94617-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short novel route to heteroyohimbine alkaloids is described. The key step in the process is the alkylation of a meso-ketone, during which its symmetry is broken. When chiral lithium amide bases are used for the ketone deprotonation encouraging levels of enantioselectivity are observed. © 1990.

引用

页码：739 / 742

页数：4

共 12 条

[1]

BERTZ SH, 1985, ORG SYNTH, V64, P27

[2] CONVERSION OF SECOLOGANIN INTO ELENOLIC ACID AND 18-OXAYOHIMBAN ALKALOIDS [J].