VARIATION IN FOOT-AND-MOUTH-DISEASE VIRUS ISOLATES IN KENYA - AN EXAMINATION OF FIELD ISOLATES BY T1 OLIGONUCLEOTIDE FINGERPRINTING

被引：9

作者：

ANDERSON, EC ^{[1
]}

UNDERWOOD, BO ^{[1
]}

BROWN, F ^{[1
]}

机构：

[1] WELLCOME INST RES FMD, EMBAKASI, KENYA

来源：

VETERINARY MICROBIOLOGY | 1985年 / 10卷 / 05期

关键词：

D O I：

10.1016/0378-1135(85)90023-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

T1 oligonucleotide maps of strains of 4 of the endemic serotypes of foot-and-mouth disease virus isolated in Kenya between 1964 and 1982 were compared with data obtained in complement-fixation and neutralization tests. There was a continual change in the oligonucleotide maps obtained for all the serotypes examined. This genetic heterogeneity was generally associated with antigenic variation. Viruses isolated during the 12-mo. course of an epidemic of the SAT 1 serotype showed few changes in their oligonucleotide fingerprints, and were serologically related. These maps form a data base that will be useful in future epidemiological studies on the maintenance and spread of foot-and-mouth disease virus in this region.

引用

页码：409 / 423

页数：15

共 13 条

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