ISOLATION AND STRUCTURE ELUCIDATION OF ERYLUSAMINE-B, A NEW CLASS OF MARINE NATURAL-PRODUCTS, WHICH BLOCKED AN IL-6 RECEPTOR, FROM THE MARINE SPONGE ERYLUS-PLACENTA THIELE

被引：21

作者：

FUSETANI, N

SATA, N

ASAI, N

MATSUNAGA, S

机构：

[1] Laboratory of Marine Biochemistry, Faculty of Agriculture The University of Tokyo, Bunkyo-ku, Tokyo

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(00)60617-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Erylusamine B(1) has been isolated as an IL-6 antagonist from the marine sponge Erylus placenta Thiele. Its structure was determined by spectral and chemical methods to be N-(5-N, N-dimethylaminopentyl)-14-oxo-22-hydroxy-25-methyl-23-O-1beta-D-xylopyranosyl-(2 --> 1)-(4-O-acetyl-beta-L-arabinopyranosyl)-(3 --> 1)-beta-D-xylopyranosyl-(4 --> 1)-2,3,4-O-triacetyl-beta-L-arabinopyranosyl)-hexacosamide.

引用

页码：4067 / 4070

页数：4

共 7 条

[1] STRUCTURE ELUCIDATION OF THE ANTIBIOTIC DESERTOMYCIN THROUGH THE USE OF NEW TWO-DIMENSIONAL NMR TECHNIQUES [J].