CUTANEOUS LEISHMANIASIS IN INDIA - CLINICAL-EXPERIENCE WITH ITRACONAZOLE (R51-211 JANSSEN)

被引:54
作者
DOGRA, J [1 ]
ANEJA, N [1 ]
LAL, BB [1 ]
MISHRA, SN [1 ]
机构
[1] SP MED COLL,DEPT MED & DERMATOL,BIKANER,INDIA
关键词
D O I
10.1111/j.1365-4362.1990.tb02593.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Abstract: Fifteen patients with cutaneous leishmaniasis were randomly selected for clinical trials with itraconazole. A single daily itraconazole dose of approximately 4 mg per 1 kg of body weight was administered to each patient with breakfast for 6 weeks. Five patients served as controls. On completion of therapy, ten cases in the study group (66.6%) were considered to be cured. No major adverse effects were reported. No significant changes were seen in the controls at the end of the study. The possibility of spontaneous recovery will be discussed in this report even though it is considered to be unlikely. Itraconazole has promising potential in cutaneous leishmaniasis therapy. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码:661 / 662
页数:2
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