GENOTYPING OF MITOCHONDRIAL ALDEHYDE DEHYDROGENASE LOCUS OF NATIVE-AMERICAN INDIANS

被引：27

作者：

ODOWD, BF

ROTHHAMMER, F

ISRAEL, Y

机构：

[1] ADDICT RES FDN,TORONTO M5S 2S1,ONTARIO,CANADA

[2] UNIV CHILE,FAC MED,DEPT CELL BIOL & GENET,SANTIAGO,CHILE

来源：

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH | 1990年 / 14卷 / 04期

关键词：

Aldehyde Dehydrogenase; American Indian; Genotyping; Hair Root; Polymerase Chain Reaction;

D O I：

10.1111/j.1530-0277.1990.tb01194.x

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Using the polymerase chain reaction to amplify genomic DNA from hair roots, we have examined the mitochondrial aldehyde dehydrogenase (ALDH2) genotypes of 28 individuals from the South American Mapuche Indians. We have determined that individuals from this population previously reported to lack (ALDH2) activity do not show the presence of the inactive (ALDH22) allele frequently found in Orientals. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：531 / 533

页数：3

共 7 条

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