OSTEOPENIA IN PRIMARY BILIARY-CIRRHOSIS AND CIRRHOSIS OF THE LIVER IN WOMEN, EVALUATED BY DUAL-ENERGY X-RAY ABSORPTIOMETRY

被引:18
作者
SHIOMI, S
KUROKI, T
MASAKI, K
TAKEDA, T
NISHIGUCHI, S
NAKAJIMA, S
SEKI, S
KOBAYASHI, K
OKAMURA, T
OCHI, H
机构
[1] Third Department of Internal Medicine, Osaka City University Medical School, Osaka, 545, 1-5-7 Asahi-machi, Abeno-ku
[2] Division of Nuclear Medicine, Osaka City University Medical School, Osaka, 545, 1-5-7 Asahi-machi, Abeno-ku
关键词
PRIMARY BILIARY CIRRHOSIS; BONE DISEASE; DUAL-ENERGY X-RAY ABSORPTIOMETRY; SINGLE-PHOTON ABSORPTIOMETRY;
D O I
10.1007/BF02365443
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
To study bone involvement in primary biliary cirrhosis (PBC), we used dual-energy X-ray absorptiometry to measure bone mineral density (BMD) in Japanese women with PBC and with cirrhosis of the liver. In both groups, in each decade up to 60 years of age, the mean BMD of the lumbar spine was not significantly different from that in healthy Japanese women; however, in patients aged 60 years or more, the level was significantly lower both in the patients with PBC (P < 0.001) and in those with cirrhosis of the liver (P < 0.01). Patients with PBC were also examined by single-photon absorptiometry. The BMD of the radius in the patients with PBC was less changed than that of the lumbar vertebrae; thus, the bone changes in PBC seem to be greater in spongy than in cortical bone.
引用
收藏
页码:605 / 609
页数:5
相关论文
共 19 条
  • [1] Atkinson M., Nordin B.E.C., Sherlock S., Malabsorption and bone disease in prolonged obstructive jaundice, Q J Med, 25, pp. 299-312, (1956)
  • [2] Long R.G., Meinhard E., Skinner R.K., Et al., Clinical, biochemical, and histological studies of osteomalacia osteoporosis, and parathyroid function in chronic liver disease, Gut, 19, pp. 85-90, (1978)
  • [3] LeBlanc A.D., Evans H.J., Marsh C., Et al., Precision of dual photon absorptiometry measurements, J Nucl Med, 27, pp. 1362-1365, (1986)
  • [4] Cullum I.D., Ell P.J., Ryder J.P., X-ray dual-photon absorptiometry: A new method for the measurement of bone density, Br J Radiol, 62, pp. 587-592, (1989)
  • [5] Mazess R.B., Collick B., Trempe J., Et al., Performance evaluation of a dual-energy X-ray bone densitometer, Calcif Tissue Int, 44, pp. 228-232, (1989)
  • [6] Thorson L.M., Wahner H.W., Single- and dual-photon absorptiometry techniques for bone mineral analysis, J Nucl Med Technol, 14, pp. 163-171, (1986)
  • [7] Sorenson J.A., Cameron J.R., A reliable in vivo measurement of bone-mineral content, J Bone Joint Surg, 49, pp. 481-497, (1967)
  • [8] Brown J.P., Delmas P.D., Malaval L., Et al., Serum bone Gla-protein: A specific marker for bone formation in postmenopausal osteoporosis, Lancet, 1, pp. 1091-1093, (1984)
  • [9] Kushida K., Inoue T., Sumi Y., Et al., Osteoporosis: Bone mineral measurement using DEXA, Jpn J Clin Med, 48, pp. 2845-2850, (1990)
  • [10] Kato Y., Epstein O., Dick R., Sherlock S., Radiological patterns of cortical bone modeling in women with chronic liver disease, Clin Radiol, 33, pp. 313-317, (1913)