THE HETEROGENEITY OF THE GERMINATIVE COMPARTMENT IN HUMAN EPIDERMIS AND ITS IMPLICATIONS IN PATHOGENESIS

被引：9

作者：

LAPORTE, M

HEENEN, M

机构：

来源：

DERMATOLOGY | 1994年 / 189卷 / 04期

关键词：

EPIDERMIS; STEM CELLS; TRANSIT CELL; PSORIASIS;

D O I：

10.1159/000246875

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Ln mouse epidermis keratinocytes of the basal layer seem to belong to 3 different subpopulations: stem cells, transit cells and postmitotic cells, Each subpopulation assumes a specific role in epidermal homeostasis, Recent data tend to display a similar heterogeneity among basal keratinocytes in human epidermis, This concept opens the door to an integrated understanding of epidermal renewal but also suggests new hypotheses in pathogenesis, Psoriasis, a typical example of epidermal hyperplasia, is considered from this point of view.

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页码：340 / 343

页数：4

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