PNEUMOCYSTIS-CARINII PNEUMONIA AS A COMPLICATION OF METHOTREXATE TREATMENT OF ASTHMA

被引：29

作者：

KUITERT, LM

HARRISON, AC

机构：

[1] London Chest Hospital

来源：

THORAX | 1991年 / 46卷 / 12期

关键词：

D O I：

10.1136/thx.46.12.936

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A 32 year old man with chronic severe asthma, requiring maintenance oral corticosteroids, was started on a weekly dose of methotrexate. Eleven weeks later he developed Pneumocystis carinii pneumonia. In the two years following treatment there has been no recurrence while oral corticosteroid treatment has been continued. Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.

引用

收藏

页码：936 / 937

页数：2

相关论文

共 9 条

[1] RHEUMATOID-ARTHRITIS, METHOTREXATE THERAPY, AND PNEUMOCYSTIS PNEUMONIA [J].

LEFF, RL ;

CASE, JP ;

MCKENZIE, R .

ANNALS OF INTERNAL MEDICINE, 1990, 112 (09) :716-716

[2] LONG-TERM METHOTREXATE TREATMENT IN CORTICOSTEROID-DEPENDENT ASTHMA [J].

MULLARKEY, MF ;

LAMMERT, JK ;

BLUMENSTEIN, BA .

ANNALS OF INTERNAL MEDICINE, 1990, 112 (08) :577-581

[3] METHOTREXATE IN THE TREATMENT OF CORTICOSTEROID-DEPENDENT ASTHMA - A DOUBLE-BLIND CROSSOVER STUDY [J].

MULLARKEY, MF ;

BLUMENSTEIN, BA ;

ANDRADE, WP ;

BAILEY, GA ;

OLASON, I ;

WETZEL, CE .

NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (10) :603-607

[4] IMMUNOLOGICAL STUDIES OF RHEUMATOID-ARTHRITIS PATIENTS TREATED WITH METHOTREXATE [J].

OLSEN, NJ ;

CALLAHAN, LF ;

PINCUS, T .

ARTHRITIS AND RHEUMATISM, 1987, 30 (05) :481-488

[5] RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF METHOTREXATE IN STEROID-DEPENDENT ASTHMA [J].

SHINER, RJ ;

NUNN, AJ ;

CHUNG, KF ;

GEDDES, DM .

LANCET, 1990, 336 (8708) :137-140

[6] PNEUMONITIS COMPLICATING LOW-DOSE METHOTREXATE THERAPY IN RHEUMATOID-ARTHRITIS [J].

STCLAIR, EW ;

RICE, JR ;

SNYDERMAN, R .

ARCHIVES OF INTERNAL MEDICINE, 1985, 145 (11) :2035-2038

[7] LOW-DOSE METHOTREXATE TREATMENT OF RHEUMATOID-ARTHRITIS - LONG-TERM OBSERVATION OF EFFICACY AND SAFETY [J].

SZANTO, E .

CLINICAL RHEUMATOLOGY, 1989, 8 (03) :323-330

[8] PNEUMOCYSTIS-CARINII PNEUMONIA COMPLICATING LOW-DOSE METHOTREXATE TREATMENT FOR PSORIATIC ARTHROPATHY [J].

WALLIS, PJW ;

RYATT, KS ;

CONSTABLE, TJ .

ANNALS OF THE RHEUMATIC DISEASES, 1989, 48 (03) :247-249

[9] PNEUMOCYSTIS-CARINII PNEUMONIA COMPLICATING LOW-DOSE METHOTREXATE TREATMENT FOR RHEUMATOID-ARTHRITIS [J].

WOLLNER, A ;

MOHLEBOETANI, J ;

LAMBERT, RE ;

PERRUQUET, JL ;

RAFFIN, TA ;

MCGUIRE, JL .

THORAX, 1991, 46 (03) :205-207