ENANTIOSELECTIVE REDUCTION OF ACETOPHENONE WITH 1,3,2-OXAZABOROLIDINES DERIVED FROM EPHEDRINE, PSEUDOEPHEDRINE, AND PHENYLGLYCINE

被引：32

作者：

BERENGUER, R ^{[1
]}

GARCIA, J ^{[1
]}

GONZALEZ, M ^{[1
]}

VILARRASA, J ^{[1
]}

机构：

[1] UNIV BARCELONA 3,FAC CHEM,DEPT ORGAN CHEM,E-08028 BARCELONA,SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 01期

关键词：

D O I：

10.1016/S0957-4166(00)86005-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The performance of several 1,3,2-oxazaborolidines as chiral catalysts in the reduction of acetophenone has been compared, to gain insight into the more relevant structural factors as far as yield and enantioselectivity are concerned. B-Alkyl-4,5,5-triphenyl-1,3,2-oxazaborolidines have emerged as effective catalysts for this reaction when nitrogen is not substituted. The origin of the enantioselectivity for this kind of catalysts is discussed.

引用

页码：13 / 16

页数：4

共 16 条

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