COPURIFICATION OF A SMALL RNA SPECIES WITH MULTICATALYTIC PROTEINASE (PROTEASOME) FROM RAT-LIVER

被引：24

作者：

SKILTON, HE

EPERON, IC

RIVETT, AJ

机构：

[1] Department of Biochemistry, University of Leicester, Leicester

来源：

FEBS LETTERS | 1991年 / 279卷 / 02期

基金：

英国惠康基金;

关键词：

MULTICATALYTIC PROTEINASE; PROTEASOME; RNA;

D O I：

10.1016/0014-5793(91)80185-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Previous studies have come to different conclusions about the presence of RNA in particles known variously as prosomes, proteasomes or multicatalytic proteinase (MCP). To determine the reason for this, MCP was isolated from rat liver by 4 different purification protocols. One major band of RNA, about 80 nucleotides in length, co-purified in all preparations. The amount of RNA detected was less than one molecule per MCP particle suggesting that there may be more than one population of MCP in rat liver cells.

引用

页码：351 / 355

页数：5

共 28 条

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