SEQUENCE OF A NEWLY IDENTIFIED MYCOBACTERIUM-TUBERCULOSIS GENE ENCODING A PROTEIN WITH SEQUENCE HOMOLOGY TO VIRULENCE-REGULATING PROTEINS

被引：23

作者：

GUPTA, S ^{[1
]}

TYAGI, AK ^{[1
]}

机构：

[1] UNIV DELHI,DEPT BIOCHEM,S CAMPUS,BENITO JUAREZ RD,NEW DELHI 110021,INDIA

来源：

GENE | 1993年 / 126卷 / 01期

关键词：

CELL ADHESION; DIDEOXY SEQUENCING; HOST INVASION; ADHESINS; MICROBIAL PATHOGENICITY; RECOMBINANT DNA;

D O I：

10.1016/0378-1119(93)90607-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Analysis of the nucleotide sequence of a gene cloned from a Mycobacterium tuberculosis H37Rv genomic library predicted a 339-amino-acid protein with an M(r) of 37656. The protein exhibited significant homology with the Cfad, FapR and Rns proteins from different enterotoxigenic strains of Escherichia coli, VirF protein of Shigella and VirFy protein of Yersinia, all of which regulate virulence-associated genes.

引用

页码：157 / 158

页数：2

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