INTERACTION OF WATER-SOLUBLE PORPHYRINS WITH SINGLE-STRANDED AND DOUBLE-STRANDED POLYRIBONUCLEOTIDES

被引:50
作者
BUSTAMANTE, C
GURRIERI, S
PASTERNACK, RF
PURRELLO, R
RIZZARELLI, E
机构
[1] SWARTHMORE COLL,DEPT CHEM,SWARTHMORE,PA 19081
[2] UNIV CATANIA,DIPARTIMENTO SCI CHIM,I-95125 CATANIA,ITALY
[3] CNR,IST STUDIO SOSTANZE NAT INTERESSE ALIMENTARE & CH,CATANIA,ITALY
关键词
D O I
10.1002/bip.360340813
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
CD and uv-visible absorption studies with several tetracationic water-soluble porphyrin derivatives show that some of these species can serve as probes to discriminate between A- and B-conformational forms of single-stranded polynucleotides. It is also observed that these porphyrins can participate in the formation of double helices by forming transient intermediate complexes enroute to duplex formation. (C) 1994 John Wiley & Sons, Inc.
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页码:1099 / 1104
页数:6
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