DNA MARKER D11S384 SHOWS ZERO RECOMBINATION WITH THE ATAXIA-TELANGIECTASIA LOCUS IN NORTH-AMERICAN FAMILIES

被引：2

作者：

LENCH, NJ

ATHMA, P

OTTAIANO, A

SRIBNEY, WM

HIGHSMITH, E

SWIFT, M

机构：

[1] NEW YORK MED COLL,DIV HUMAN MOLEC GENET,VALHALLA,NY 10595

[2] NEW YORK MED COLL,INST GENET ANAL COMMON DIS,VALHALLA,NY 10595

[3] NEW YORK MED COLL,DEPT PEDIAT,VALHALLA,NY 10595

[4] APPL TECHNOL GENET CORP,MALVERN,PA

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY | 1994年 / 66卷 / 06期

关键词：

D O I：

10.1080/09553009414551881

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.

引用

页码：S67 / S69

页数：3

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