RADIOIMMUNOASSAY PROCEDURES FOR ASTEMIZOLE AND METABOLITES IN PLASMA

被引：19

作者：

WOESTENBORGHS, R

GEUENS, I

MICHIELS, M

HENDRIKS, R

HEYKANTS, J

机构：

来源：

DRUG DEVELOPMENT RESEARCH | 1986年 / 8卷 / 1-4期

关键词：

D O I：

10.1002/ddr.430080108

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：63 / 69

页数：7

共 7 条

[1]

AWOUTERS FHL, 1983, ARZNEIMITTEL-FORSCH, V33-1, P381

[2] DOSE-PROPORTIONALITY, BIOAVAILABILITY, AND STEADY-STATE KINETICS OF ASTEMIZOLE IN MAN [J].

HEYKANTS, J ;

VANPEER, A ;

WOESTENBORGHS, R ;

JAGENEAU, A ;

VANDENBUSSCHE, G .

DRUG DEVELOPMENT RESEARCH, 1986, 8 (1-4) :71-78

[3] EXCRETION AND BIOTRANSFORMATION OF ASTEMIZOLE IN RATS, GUINEA-PIGS, DOGS, AND MAN [J].

MEULDERMANS, W ;

HENDRICKX, J ;

LAUWERS, W ;

HURKMANS, R ;

SWYSEN, E ;

HEYKANTS, J .

DRUG DEVELOPMENT RESEARCH, 1986, 8 (1-4) :37-51

[4] PHARMACOKINETICS AND TISSUE DISTRIBUTION OF ASTEMIZOLE IN THE DOG [J].

MICHIELS, M ;

VANPEER, A ;

WOESTENBORGHS, R ;

HEYKANTS, J .

DRUG DEVELOPMENT RESEARCH, 1986, 8 (1-4) :53-62

[5] SYNTHESIS OF H-3-LABELED AND C-14-LABELED ASTEMIZOLE (R-43-512) [J].

THIJSSEN, JBA ;

KNAEPS, AG ;

HEYKANTS, JJP .

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1983, 20 (07) :861-868

[6]

VANWAUWE J, 1981, ARCH INT PHARMACOD T, V251, P39

[7] SIMULTANEOUS DETERMINATION OF ASTEMIZOLE AND ITS DEMETHYLATED METABOLITE IN ANIMAL PLASMA AND TISSUES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

WOESTENBORGHS, R ;

EMBRECHTS, L ;

HEYKANTS, J .

JOURNAL OF CHROMATOGRAPHY, 1983, 278 (02) :359-366

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