A G-RICH SEQUENCE ELEMENT COMMON TO DICTYOSTELIUM GENES WHICH DIFFER RADICALLY IN THEIR PATTERNS OF EXPRESSION

被引：32

作者：

CECCARELLI, A

MAHBUBANI, HJ

INSALL, R

SCHNITZLER, G

FIRTEL, RA

WILLIAMS, JG

机构：

[1] IMPERIAL CANC RES FUND,CLARE HALL LABS,POTTERS BAR 3EN 6LD,HERTS,ENGLAND

[2] UNIV CALIF SAN DIEGO,DEPT BIOL,CTR MOLEC GENET,LA JOLLA,CA 92037

来源：

DEVELOPMENTAL BIOLOGY | 1992年 / 152卷 / 01期

关键词：

D O I：

10.1016/0012-1606(92)90169-H

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Removal of a G-rich element from the DIF-inducible, prestalk-, and stalk-specific ecmB gene reduces expression but cell-type specificity is retained. The ecmB element will functionally substitute for a homologous sequence upstream of CP2, a cAMP-inducible gene and is bound by GBF, the factor which interacts with the CP2 G box. These results suggest that the G box may play a similar stimulatory role in these two independently regulated genes where it presumably interacts with different ancillary promoter elements. © 1992.

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页码：188 / 193

页数：6

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