VIC-TRIAZOLINES .34. THERMAL-BEHAVIOR OF 1-(2-AMINOPHENYL)-4,5-DIHYDRO-5-MORPHOLINO-1,2,3-TRIAZOLES - NEW SYNTHESIS OF 2-ALKYLQUINOXALINES

被引：20

作者：

BATTISTINI, M ^{[1
]}

ERBA, E ^{[1
]}

POCAR, D ^{[1
]}

机构：

[1] UNIV MILAN,FAC FARM,IST CHIM ORGAN,VIA VENEZIAN 21,I-20133 MILAN,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 03期

关键词：

D O I：

10.1039/p19930000339

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4,5-Dihydro-5-morpholino-1-(2-nitrophenyl)-1,2,3-triazoles 4 are prepared by reaction of an aldehyde with morpholine and the appropriate aryl azide. On reduction 1-(2-aminophenyl)-4,5-dihydro-5-morpholino-1,2,3-triazoles 5 are formed. Thermal rearrangement of compounds 5 affords unstable 2-alkyl-3-amino-1,2,3,4-tetrahydroquinoxalines 7, which undergo deamination to 2-alkyl-1,2-dihydroquinoxalines 8. Oxidation of these affords 2-alkylquinoxalines 1 0. The mechanism of the thermal rearrangement of triazoles 5 is investigated and discussed.

引用

页码：339 / 342

页数：4

共 13 条

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