CLINICAL-EVALUATION OF DRUG EFFICACY IN UTI IN MEN - THE SIGNIFICANCE OF BACTERIAL ELIMINATION ON DAY ONE

被引:2
作者
ARAKAWA, S
KAMIDONO, S
机构
[1] Dept. of Urology, Kobe University School of Medicine, Kobe City, Hyogo, Kusonoki-cho 7-5-2, Chuo-ku
关键词
D O I
10.1007/BF01716033
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
With the purpose of assessing whether the effect of a drug at an early stage of administration could serve to predict efficacy at the end of drug treatment, a cephem antibiotic was administered for 5 days (days 0-4) by injection in males with complicated UTI. Results showed that the bacteriological effect on day 1 was reflected in the overall clinical efficacy on day 5. The activity of an antibacterial agent appeared to be reflected in the ability to eliminate bacteria 1 to 2 days after the start of drug administration.
引用
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页码:S23 / S26
页数:4
相关论文
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[1]  
OHKOSKI M, 1987, JAP J ANTIBIOTICS, V49, P2149