SYNTHESIS AND ANTITUMOR ACTIVITY OF 1,2-DIHYDRO-1-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)-2-OXO-5-METHYLPYRAZINE 4-OXIDE, A STRUCTURAL ANALOG OF THYMIDINE

被引：17

作者：

BOBEK, M

BLOCH, A

BERKOWITZ, P

BARDOS, TJ

机构：

[1] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,DEPT EXPTL THERAPEUT,BUFFALO,NY 14263

[2] NEW YORK STATE DEPT HLTH,ROSWELL PK MEM INST,GRACE CANC DRUG CTR,BUFFALO,NY 14263

[3] SUNY BUFFALO,DEPT MED CHEM,BUFFALO,NY 14214

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1977年 / 20卷 / 03期

关键词：

D O I：

10.1021/jm00213a029

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：458 / 460

页数：3

共 11 条

[1] SYNTHESIS OF 1,2-DIHYDRO-1-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)-22-OXOPYRAZINE 4-OXIDE, A POTENT ANALOG OF DEOXYURIDINE
BERKOWITZ, PT
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[2] BHAT CC, 1968, SYNTHETIC PROCEDURES, V1, P521
[3] INHIBITION OF PROTEIN SYNTHESIS BY 5'-SULFAMOYLADENOSINE
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[4] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRAZINES AND PYRAZINE RIBONUCLEOSIDES AS PYRIMIDINE ANALOGS
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[5] SYNTHESIS OF 5-S-SUBSTITUTED 2'-DEOXYURIDINES . STUDY OF FACTORS INFLUENCING STEREOSELECTIVITY OF SILYL MODIFICATION OF HILBERT-JOHNSON REACTION
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[6] CHEMICAL SYNTHESIS OF 2'-DEOXY-5-(TRIFLUOROMETHYL)URIDINE AND ALPHA ANOMER
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[7] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME IMIDAZO[4,5-B]PYRAZINES AND THEIR RIBONUCLEOSIDES AS PURINE ANALOGS
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COLE, FE
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (06) : 643 - 647
[8] TOWNSEND LB, 1973, SYNTHETIC PROCEDURES, V2, P267
[9] WATANABE KA, 1976, J CARBOHYDR NUCLEOSI, V1, P1
[10] PYRIMIDINE NUCLEOSIDES .I. SYNTHESIS OF 6-METHYLCYTIDINE 6-METHYLURIDINE AND RELATED 6-METHYLPYRIMIDINE NUCLEOSIDES
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