AROMATICITY IN HETEROCYCLIC SYSTEMS .V. BROMINATION STUDIES OF CERTAIN PURINES PYRROLO[3,2-D] PYRIMIDINES AND PYRAZOLO[4,3-D]PYRIMIDINES

被引：16

作者：

CASSIDY, F

OLSEN, RK

ROBINS, RK

机构：

[1] Department of Chemistry, University of Utah

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1968年 / 5卷 / 04期

关键词：

D O I：

10.1002/jhet.5570050404

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bromination of certain selected purines, pyrrolo[3,2‐d]pyrimidines and pyrazolo[4,3‐d]‐pyrimidines has been studied and the reactivity of these systems compared. Displacement of a carboxyl group by bromine was noted in the case of 6‐carboxypyrrolo[3,2‐d]‐2,4‐pyrimidinedione. In contrast to xanthine, 2,6‐diethoxypurine readily brominated at position 8. Pyrazolo‐[4,3‐d]‐7‐pyrimidone was readily brominated at position 3. Copyright © 1968 Journal of Heterocyclic Chemistry

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页码：461 / &

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