INTRAMOLECULAR CYCLIZATION-N-DEALKYLATION OF AZETIDINE-3-ACETIC ACIDS

被引：5

作者：

BARTHOLOMEW, D

STOCKS, MJ

机构：

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)92311-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Aryl-azetidine-3-acetic acids are converted to pyrrolidinones when treated with oxalyl chloride. The intramolecular cyclisation-N-dealkylation reaction occurs via an azabicyclic intermediate. N-Aryl-azetidine-3-acetic acids are prepared from N-aryl-3-(chloromethyl)azetidin-2-ones.

引用

页码：4799 / 4800

页数：2

共 5 条

[1]

BARTHOLOMEW D, 1991, TET LETT

[2] INTRAMOLECULAR REACTION OF ACID CHLORIDE AND TERTIARY AMINE GROUPS [J].