ISCHEMIC STROKE DUE TO PROTEIN-C DEFICIENCY

被引：70

作者：

KOHLER, J ^{[1
]}

KASPER, J ^{[1
]}

WITT, I ^{[1
]}

VONREUTERN, GM ^{[1
]}

机构：

[1] UNIV FREIBURG,DEPT PEDIAT,W-7800 FREIBURG,GERMANY

来源：

STROKE | 1990年 / 21卷 / 07期

关键词：

Arterial occlusive disease; Cerebral ischemia; Protein C;

D O I：

10.1161/01.STR.21.7.1077

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Plasma protein C exerts anticoagulatory effects by inactivating factors V and VIII. Hereditary protein C deficiency is transmitted as an autosomal dominant disorder. Homozygous individuals usually develop purpura fulminans as newborns; heterozygous protein C-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism. However, arterial thrombosis has been only rarely observed. We describe a young patient with heterozygous protein C deficiency who experienced a severe stroke due to thrombotic occlusion of the left middle cerebral artery. © 1990 American Heart Association, Inc.

引用

页码：1077 / 1080

页数：4

共 16 条

[1] ISCHEMIC STROKE IN ADULTS YOUNGER THAN 30 YEARS OF AGE - CAUSE AND PROGNOSIS [J].