CHANGES IN BODY-TEMPERATURE MARKEDLY AFFECT STRIATAL DOPAMINE RELEASE AND METABOLISM - AN INVIVO STUDY

被引：12

作者：

BRANNAN, T ^{[1
]}

MARTINEZTICA, J ^{[1
]}

YAHR, MD ^{[1
]}

机构：

[1] CUNY MT SINAI SCH MED,DEPT NEUROL,NEW YORK,NY 10029

来源：

JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1992年 / 89卷 / 03期

关键词：

DOPAMINE; BODY TEMPERATURE; PARKINSONS DISEASE; CEREBRAL MICRODIALYSIS;

D O I：

10.1007/BF01250671

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Dopamine release and metabolism in the corpus striatum increased markedly when the core body temperature of anesthetized rats was increased from 35-degrees to 41-degrees-C while temperatures below 34-degrees were associated with a marked attenuation of dopamine release. These observations may have clinical relevance in cases where alterations in body temperature are associated with extrapyramidal dysfunction.

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页码：193 / 196

页数：4

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