EFFECT OF HEAD PHANTOM SIZE ON B-10 AND H-1[N,GAMMA]H-2 DOSE DISTRIBUTIONS FOR A BROAD FIELD ACCELERATOR EPITHERMAL NEUTRON SOURCE FOR BNCT

被引:10
作者
GUPTA, N
NIEMKIEWICZ, J
BLUE, TE
GAHBAUER, R
QU, TX
机构
[1] RIVERSIDE METHODIST HOSP,DEPT RADIAT ONCOL,COLUMBUS,OH 43214
[2] OHIO STATE UNIV,ARTHUR JAMES CANC HOSP,DEPT RADIAT ONCOL,COLUMBUS,OH 43210
关键词
BNCT; MONTE-CARLO; POINT KERNEL;
D O I
10.1118/1.597131
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The effect of head phantom size on the B-10 and H-1[n,gamma]H-2 dose distributions for a broad epithermal neutron radiation field generated by an accelerator-based epithermal neutron source for boron neutron capture therapy (BNCT) have been studied. Also two techniques for calculating the absorbed gamma dose from a measured gamma-ray source distribution are compared: a Monte Carlo technique, which is well accepted in the BNCT community, and a Point Kernel technique. The count-rate distribution in the central plane of three rectangular parallelopiped head water phantoms irradiated with an epithermal neutron field was measured with a boron trifluoride (BF3) detector. This epithermal neutron field was produced at the Ohio State University Van de Graaff Accelerator Facility. The B-10 absorbed dose and the gamma-ray source have the same distribution in the head phantom as the BF3 count-rate distribution. The absorbed gamma dose from the measured source distribution was calculated using MCNP, a Monte Carlo code, and QAD-CGGP, a Point Kernel code. The most pronounced effect of phantom size on B-10 absorbed dose was on the dose rate at the depth of maximum dose, d(max). An increase in dose rate at d(max) was observed with a decrease in phantom size, the dose rate in the smallest phantom being larger by a factor of 1.4 than the dose rate in the largest phantom. Also, d(max) for the phantoms shifted deeper with a decrease in phantom dimensions. The shift between the largest and the smallest phantoms was 6 mm. Finally, the smaller phantoms had lower entrance B-10 dose as a percent of the dose at d(max), or better skin sparing. Our calculations for the gamma dose show that a Point Kernel technique can be used to calculate the dose distribution as accurately as a Monte Carlo technique, in much shorter computation times.
引用
收藏
页码:395 / 404
页数:10
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