STRUCTURE-FUNCTION-RELATIONSHIPS AND MECHANISM OF ACTION OF PITUITARY AND PLACENTAL GONADOTROPINS

被引：5

作者：

APPARAILLY, F ^{[1
]}

LAURENTCADORET, V ^{[1
]}

LECOMPTE, F ^{[1
]}

CHOPINEAU, M ^{[1
]}

MAUREL, MC ^{[1
]}

GUILLOU, F ^{[1
]}

COMBARNOUS, Y ^{[1
]}

机构：

[1] INRA,CNRS,UNIT 1291,F-37380 NOUZILLY,FRANCE

来源：

REPRODUCTION FERTILITY AND DEVELOPMENT | 1994年 / 6卷 / 02期

关键词：

D O I：

10.1071/RD9940157

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Data from the author's laboratory on relationships between structure and function of equine luteinizing hormone, follicle-stimulating hormone and choriogonadotrophin as well as their mechanisms of action are reviewed and compared with their human counterparts. Polymorphism of these hormones and problems associated with their purification are discussed as well as the association and dissociation of their alpha- and beta-subunits. The affinity of receptor binding, the superactivity of membrane transduction and homologous desensitization of target cells by non-stimulatory doses of the gonadotrophins are also reviewed.

引用

页码：157 / 163

页数：7

共 38 条

[1] PURIFICATION AND CHARACTERIZATION OF LUTEINIZING-HORMONE FROM THE DROMEDARY (CAMELUS-DROMEDARIUS) [J].