STEROIDS .41. SYNTHESIS, X-RAY STRUCTURE AND MOLECULAR MECHANICS STUDIES OF THE BOAR TAINT STEROID (5-ALPHA-ANDROST-16-EN-3-ONE)

被引：22

作者：

COX, PJ ^{[1
]}

TURNER, AB ^{[1
]}

机构：

[1] UNIV ABERDEEN, DEPT CHEM, ABERDEEN AB9 2UE, SCOTLAND

来源：

TETRAHEDRON | 1984年 / 40卷 / 16期

关键词：

D O I：

10.1016/S0040-4020(01)82442-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5.alpha.-Androst-16-en-3-one was prepared from 5.alpha.-androstan-3.beta.-ol-17-one in an overall yield of 34% by the vinyl iodide route. Accurate molecular dimensions were determined by X-ray crystal structure analysis and by molecular mechanics calculations. There is significant twisting of the angular methyl groups in the molecule.

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页码：3153 / 3158

页数：6

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