OXIDATION OF SPARTEINES BY CYTOCHROME-P-450 - EVIDENCE AGAINST THE FORMATION OF N-OXIDES

被引：34

作者：

GUENGERICH, FP ^{[1
]}

机构：

[1] VANDERBILT UNIV,CTR MOLEC TOXICOL,NASHVILLE,TN 37232

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 27卷 / 09期

关键词：

D O I：

10.1021/jm00375a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：1101 / 1103

页数：3

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共 27 条

[1] AUGUSTO O, 1982, J BIOL CHEM, V257
[2] LUPIN-ALKALOIDS .41. C-13-NMR SPECTRA OF LUPIN-ALKALOIDS
BOHLMANN, F
ZEISBERG, R
[J]. CHEMISCHE BERICHTE-RECUEIL, 1975, 108 (04): : 1043 - 1051
[3] TERTIARY AMINE OXIDE REARRANGEMENTS .1. MECHANISM
CRAIG, JC
GLAZER, AN
DWYER, FP
HORNING, EC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (08) : 1871 - &
[4] DISTLERATH LM, UNPUB
[5] DEFECTIVE N-OXIDATION OF SPARTEINE IN MAN - NEW PHARMACOGENETIC DEFECT
EICHELBAUM, M
SPANNBRUCKER, N
STEINCKE, B
DENGLER, HJ
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (03) : 183 - 187
[6] DETOXICATION MECHANISMS .3. SCOPE AND MECHANISM OF IRON-CATALYZED DEALKYLATION OF TERTIARY AMINE OXIDES
FERRIS, JP
GERWE, RD
GAPSKI, GR
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (09) : 3493 - &
[7] GALINOVSKY F, 1956, MH CHEM, V87, P763
[8] PURIFICATION OF CYTOCHROME-P-450, NADPH-CYTOCHROME P-450 REDUCTASE, AND EPOXIDE HYDRATASE FROM A SINGLE PREPARATION OF RAT-LIVER MICROSOMES
GUENGERICH, FP
MARTIN, MV
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1980, 205 (02) : 365 - 379
[9] CHEMICAL MECHANISMS OF CATALYSIS BY CYTOCHROMES-P-450 - A UNIFIED VIEW
GUENGERICH, FP
MACDONALD, TL
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1984, 17 (01) : 9 - 16
[10] GUENGERICH FP, UNPUB