A REGIOSELECTIVE SYNTHESIS OF 3-ISOPRENYL-4-HYDROXYCOUMARINS

被引：14

作者：

APPENDINO, G ^{[1
]}

CRAVOTTO, G ^{[1
]}

NANO, GM ^{[1
]}

PALMISANO, G ^{[1
]}

机构：

[1] CNR,DIPARTIMENTO CHIM ORGAN & IND,CTR STUDIO SOSTANZE ORGAN NAT,I-20133 MILAN,ITALY

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 15期

关键词：

D O I：

10.1080/00397919208019073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

the dianion of ethyl 3-(2-hydroxyphenyl)-3-oxopropanoate can be regioselectively alkylated with isoprenyl bromides to give, after hydrolytic work-up, the corresponding 3-substituted-4-hydroxycoumarins.

引用

页码：2205 / 2212

页数：8

共 14 条

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APPENDINO, G
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[J]. HELVETICA CHIMICA ACTA, 1991, 74 (07) : 1451 - 1458
[2] OMEGA-OXYGENATED PRENYLATED COUMARINS FROM FERULA-COMMUNIS
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[J]. PHYTOCHEMISTRY, 1988, 27 (11) : 3619 - 3624
[3] SYNTHESIS AND PROTEIN-TYROSINE KINASE INHIBITORY ACTIVITIES OF FLAVONOID ANALOGS
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[4] GONZALEZ AG, 1981, AN QUIM C-ORG BIOQ, V77, P63
[5] GONZALEZ AG, 1983, AN QUIM C-ORG BIOQ, V79, P265
[6] KREISER W, 1987, THESIS U DORTMUND
[7] KUMAR RJ, 1990, SYNTHESIS-STUTTGART, P535
[8] MAJUMDAR KC, 1990, INDIAN J CHEM B, V29, P483
[9] COUMARINS
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[J]. NATURAL PRODUCT REPORTS, 1989, 6 (06) : 591 - 624
[10] Studies on 4-hydroxycoumarins. II. The condensation of aldehydes with 4-hydroxycoumarins
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1943, 65 : 2288 - 2291

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