TRANSITION DYNAMICS OF HIV DISEASE IN A COHORT OF AFRICAN PROSTITUTES - A MARKOV MODEL APPROACH

被引：29

作者：

NAGELKERKE, NJD

PLUMMER, FA

HOLTON, D

ANZALA, AO

MANJI, F

NGUGI, EN

MOSES, S

机构：

[1] KENYA GOVT MED RES CTR,NAIROBI,KENYA

[2] UNIV MANITOBA,DEPT MED MICROBIOL,WINNIPEG R3T 2N2,MANITOBA,CANADA

[3] INT DEV RES CTR,REG OFF EASTERN & SO AFRICA,NAIROBI,KENYA

[4] UNIV NAIROBI,DEPT COMMUNITY HLTH,NAIROBI,KENYA

来源：

AIDS | 1990年 / 4卷 / 08期

关键词：

Disease stage; Incubation time; Markov model; Prostitutes;

D O I：

10.1097/00002030-199008000-00005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The progression of HIV-related disease from infection to death is represented as a staged Markov model. Transitions between stages are considered reversible. The model is fitted to data from a cohort of African prostitutes by means of maximum likelihood. It appears that the progression to symptomatic disease (Centers for Disease Control stage IV) in this population is considerably more rapid than that reported from studies in Western countries.

引用

页码：743 / 747

页数：5

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