APOLIPOPROTEIN-E ALLELES BUT NEITHER APOLIPOPROTEIN-B NOR APOLIPOPROTEIN AI/CIII ALLELES ARE ASSOCIATED WITH LATE-ONSET, FAMILIAL ALZHEIMERS-DISEASE

被引：14

作者：

HOULDEN, H

CROOK, R

DUFF, K

HUTTON, M

COLLINGE, J

ROQUES, P

ROSSOR, M

HARDY, J

机构：

[1] ST MARYS HOSP,SCH MED,DEPT BIOCHEM,PRION RES GRP,LONDON W2 1PG,ENGLAND

[2] ST MARYS HOSP,SCH MED,DEPT NEUROL,PRION RES GRP,LONDON W2 1PG,ENGLAND

[3] ST MARYS HOSP,SCH MED,DEPT NEUROL,DEMENTIA GRP,LONDON W2 1PG,ENGLAND

[4] UNIV S FLORIDA,DEPT PSYCHIAT,SUNCOAST ALZHEIMERS DIS LABS,TAMPA,FL 33613

[5] UNIV S FLORIDA,DEPT PHARMACOL,SUNCOAST ALZHEIMERS DIS LABS,TAMPA,FL 33613

[6] UNIV S FLORIDA,DEPT NEUROL,SUNCOAST ALZHEIMERS DIS LABS,TAMPA,FL 33613

[7] UNIV S FLORIDA,DEPT BIOCHEM,SUNCOAST ALZHEIMERS DIS LABS,TAMPA,FL 33613

来源：

NEUROSCIENCE LETTERS | 1995年 / 188卷 / 03期

关键词：

ALZHEIMERS DISEASE; ASSOCIATION; GENETICS; APOLIPOPROTEIN B; APOLIPOPROTEIN AI/CIII; APOLIPOPROTEIN E;

D O I：

10.1016/0304-3940(95)11422-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The possibility of a genetic association between late onset, familial Alzheimer's disease and alleles at the apolipoprotein B and AI/CIII loci have been examined. In contrast to the genetic association with the apolipoprotein E locus, no evidence for genetic associations to these loci was found.

引用

收藏

页码：202 / 204

页数：3

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