A DESCRIPTION OF HUMAN PLACENTAL SYNCYTIOTROPHOBLAST MEMBRANE GLYCOSPHINGOLIPIDS

被引:11
作者
CHENG, HM [1 ]
JOHNSON, PM [1 ]
机构
[1] UNIV LIVERPOOL, DEPT IMMUNOL, PREGNANCY IMMUNOL GRP, POB 147, LIVERPOOL L69 3BX, ENGLAND
关键词
D O I
10.1016/S0143-4004(85)80052-7
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The glycosphingolipid (GSL) structure of isolated human term placental syncytiotrophoblast microvillous plasma membrane (StMPM) was investigated by Folch solvent extraction and thin-layer chromatography. StMPM preparations were shown to contain unique hydrophilic GSL species, including 2 highly glycosylated (> 15 saccharide residues/molecule) components. This fraction consistently included 4 major gangliosides (sialylated GSL), and 2 highly-sialylated (.gtoreq. 4 sialic acid residues/molecules) minor gangliosides.
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页码:229 / 238
页数:10
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