TARGETING OF UREA STIBAMINE ENCAPSULATED IN LIPOSOMES TO RETICULOENDOTHELIAL SYSTEM FOR THE TREATMENT OF EXPERIMENTAL LEISHMANIASIS

被引：30

作者：

DAS, N ^{[1
]}

MAHATO, SB ^{[1
]}

NASKAR, K ^{[1
]}

GHOSH, DK ^{[1
]}

BASU, MK ^{[1
]}

机构：

[1] INDIAN INST CHEM BIOL,LEISHMANIA GRP,CALCUTTA 700032,W BENGAL,INDIA

来源：

BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY | 1990年 / 43卷 / 02期

关键词：

D O I：

10.1016/0885-4505(90)90018-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The antileishmanial antimonial drug urea stibamine was encapsulated in mannosylated and nonmannosylated liposomes and was tested against experimental leishmanial infection in hamsters. The study demonstrated that liposome encapsulation of urea stibamine enhanced its effectiveness, an effect which was greater when mannosylated liposomes were used. © 1990.

引用

页码：133 / 139

页数：7

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