AUTOIMMUNITY AND THE OVARY

被引：28

作者：

MONCAYO, R ^{[1
]}

MONCAYO, HE ^{[1
]}

机构：

[1] UNIV INNSBRUCK, DEPT OBSTET & GYNECOL, A-6020 INNSBRUCK, AUSTRIA

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 07期

关键词：

D O I：

10.1016/0167-5699(92)90006-S

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The ovary was first documented as a target of autoimmunity over three decades ago yet today the aetiology and pathogenesis of autoimmune-mediated premature ovarian failure (POF) are poorly understood. Here, Roy and Helga Moncayo provide a brief overview of human autoimmune-mediated POF and the animal models of POF. They propose a model for the development of the disease, highlighting the role of supraphysiological levels of gonadotropins in inducing selectively antigenic mature ovarian elements.

引用

页码：255 / 258

页数：4

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