UNEXPECTED THERMAL EXTRUSION OF CO2 FROM 3-BENZYLTHIAZOLIDIN-2-ONE 1,1-DIOXIDES TO GIVE 2-PHENYLTHIAZOLINES AND THIAZOLES

被引：9

作者：

AITKEN, RA ^{[1
]}

ARMSTRONG, DP ^{[1
]}

MESHER, STE ^{[1
]}

机构：

[1] ZENECA PHARMACEUT,MACCLESFIELD SK10 2TG,CHESHIRE,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

D O I：

10.1016/0040-4039(94)88100-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Flash vacuum pyrolysis of a series of chiral 3-benzylthiazolidin-2-one 1,1-dioxides 5, readily prepared from amino acids, results mainly in loss of SO2 to give an alkene and benzyl isocyanate, but a significant minor pathway involves unexpected loss of CO2 and water to give 2-phenylthiazolines 13 and derived thiazoles.

引用

页码：6143 / 6146

页数：4

共 14 条

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[8]

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