SELF-ASSOCIATION OF AMPHIPHILIC PHENOTHIAZINE DRUGS IN AQUEOUS-SOLUTIONS OF LOW IONIC-STRENGTH

被引：15

作者：

ATTWOOD, D ^{[1
]}

MOSQUERA, V ^{[1
]}

REY, C ^{[1
]}

VASQUEZ, E ^{[1
]}

机构：

[1] UNIV SANTIAGO DE COMPOSTELA,FAC FIS,DEPT FIS MAT CONDENSADA,SANTIAGO,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS | 1991年 / 87卷 / 18期

关键词：

D O I：

10.1039/ft9918702971

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Osmotic coefficients have been derived from freezing point determinations on aqueous solutions of the amphiphilic drugs, chlorpromazine and promethazine hydrochloride, in the presence of low concentrations of added electrolyte (0.01-0.05 mol kg-1 NaCl). Aggregation numbers predicted by the application of a mass action theory to the osmotic data were in agreement with experimental values determined by time-averaged light scattering methods.

引用

页码：2971 / 2973

页数：3

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