2 TYPES OF RECEPTORS FOR IRON ON MITOCHONDRIA

被引：16

作者：

WEAVER, J ^{[1
]}

POLLACK, S ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MED,DIV HEMATOL,1300 MORRIS PK AVE,BRONX,NY 10461

来源：

BIOCHEMICAL JOURNAL | 1990年 / 271卷 / 02期

关键词：

D O I：

10.1042/bj2710463

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ATP, the major ligand for Fe in the reticulocyte's low-M(r) chelatable pool, transfers Fe to a mitochondrial receptor from which the Fe is incorporated into haem. However, the utilization of Fe bound to this receptor for haem synthesis is slow in comparison with that bound to a second receptor that does not accept Fe from ATP, but does accept it from AMP. The major pathway by which Fe is delivered for haem synthesis may be through hydrolysis of cytosolic ATP-Fe to AMP-Fe.

引用

页码：463 / 466

页数：4

共 21 条

[1] UTILIZATION OF IRON AND ITS COMPLEXES BY MAMMALIAN MITOCHONDRIA
BARNES, R
CONNELLY, JL
JONES, OTG
[J]. BIOCHEMICAL JOURNAL, 1972, 128 (05) : 1043 - +
[2] A COMPARATIVE-STUDY ON IRON SOURCES FOR MITOCHONDRIAL HEME-SYNTHESIS INCLUDING FERRITIN AND MODELS OF TRANSIT POOL SPECIES
FUNK, F
LECRENIER, C
LESUISSE, E
CRICHTON, RR
SCHNEIDER, W
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1986, 157 (02): : 303 - 309
[3] GOUCHER CR, 1964, J BIOL CHEM, V239, P2251
[4] Johnson D., 1967, METH ENZYMOL, V10, P94, DOI [10.1016/0076-6879(67)10018-9, DOI 10.1016/0076-6879(67)10018-9]
[5] HYDROLYSIS OF PHOSPHATE-ESTERS BOUND TO COBALT(III) - KINETICS AND MECHANISM OF INTRAMOLECULAR ATTACK OF HYDROXIDE ON COORDINATED 4-NITROPHENYL PHOSPHATE
JONES, DR
LINDOY, LF
SARGESON, AM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (25) : 7327 - 7336
[6] STUDIES ON THE MECHANISM OF PYROPHOSPHATE-MEDIATED UPTAKE OF IRON FROM TRANSFERRIN BY ISOLATED RAT-LIVER MITOCHONDRIA
KONOPKA, K
ROMSLO, I
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1981, 117 (02): : 239 - 244
[7] KONOPKA K, 1980, EUR J BIOCHEM, V107, P433
[8] TRANSFERRIN AS A DONOR OF IRON TO MITOCHONDRIA - EFFECT OF PYROPHOSPHATE AND RELATIONSHIP TO MITOCHONDRIAL METABOLISM AND HEME-SYNTHESIS
NILSEN, T
ROMSLO, I
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 802 (03) : 448 - 453
[9] PYROPHOSPHATE AS A LIGAND FOR DELIVERY OF IRON TO ISOLATED RAT-LIVER MITOCHONDRIA
NILSEN, T
ROMSLO, I
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 766 (01) : 233 - 239
[10] NUNEZ MT, 1989, BLOOD S1, V74, pA61

← 1 2 3 →