MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE GENE OF THE MOLYBDENUM-CONTAINING ALDEHYDE OXIDOREDUCTASE OF DESULFOVIBRIO-GIGAS - THE DEDUCED AMINO-ACID-SEQUENCE SHOWS SIMILARITY TO XANTHINE DEHYDROGENASE

被引：50

作者：

THOENES, U

FLORES, OL

NEVES, A

DEVREESE, B

VANBEEUMEN, JJ

HUBER, R

ROMAO, MJ

LEGALL, J

MOURA, JJG

RODRIGUESPOUSADA, C

机构：

[1] GULBENKIAN INST SCI,GENET MOLEC LAB,OEIRAS,PORTUGAL

[2] VAKGRP BIOCHEM FYSIOL & MICROBIOL,GHENT,BELGIUM

[3] INST SUPER TECN,DEPT QUIM,LISBON,PORTUGAL

[4] INST TECNOL QUIM & BIOL,OEIRAS,PORTUGAL

[5] UNIV NOVA LISBOA,FCT,DEPT QUIM,MONTE DE CAPARICA,PORTUGAL

[6] UNIV GEORGIA,DEPT BIOCHEM,ATHENS,GA

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1994年 / 220卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1994.tb18693.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this report, we describe the isolation of a 4020-bp genomic PstI fragment of Desulfovibrio gigas harboring the aldehyde oxido-reductase gene. The aldehyde oxido-reductase gene spans 2718 bp of genomic DNA and codes for a protein with 906 residues. The protein sequence shows an average 52% (+/- 1.5%) similarity to xanthine dehydrogenase from different organisms. The codon usage of the aldehyde oxidoreductase is almost identical to a calculated codon usage of the Desulfovibrio bacteria.

引用

页码：901 / 910

页数：10

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