COMPARISON OF SEROEPIDEMIOLOGY OF HEPATITIS-C IN BLOOD-DONORS BETWEEN BANGLADESH AND JAPAN

被引:19
作者
KHAN, M [1 ]
HUSAIN, M [1 ]
YANO, M [1 ]
HASHIZUME, K [1 ]
YOUSUF, M [1 ]
TANAKA, E [1 ]
MATSUMOTO, A [1 ]
FURUTA, S [1 ]
KIYOSAWA, K [1 ]
机构
[1] SHINSHU UNIV,SCH MED,DEPT INTERNAL MED 2,MATSUMOTO,NAGANO 390,JAPAN
来源
GASTROENTEROLOGIA JAPONICA | 1993年 / 28卷
关键词
D O I
10.1007/BF02989200
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
To compare the seroepidemiology of hepatitis C and hepatitis B between Bangladesh and Japan, we tested the second generation antibody to hepatitis C virus (anti-HCV-2) and hepatitis B surface antigen (HBsAg) in serum samples from 163 professional blood donors (161 males and 2 females, mean age 28.6 yr.) and 83 voluntary blood donors from Bangladesh, and 7479 Japanese voluntary blood donors (5036 males and 2443 females; mean age 37.1 yr.). In Bangladesh, anti-HCV-2 is detected in 2.4% of professional blood donors and 0% of voluntary blood donors, furthermore, HBsAg is detected in 29% and in 2.4% of professional and voluntary blood donors, respectively. In Japan, anti-HCV-2 is detected in 0.6% in voluntary blood donors, and HBsAg also in 0.6%. These results indicate that professional blood donors in Bangladesh are highly contaminated by hepatitis B virus and moderately by hepatitis C virus, while voluntary blood donors in both countries are not so highly contaminated by either hepatitis viruses. © 1993 The Japanese Society of Gastroenterology.
引用
收藏
页码:28 / 31
页数:4
相关论文
共 9 条
  • [1] Choo Q.L., Kuo G., Weiner A.J., Et al., Isolation of a cDNA clone derived from a bloodborn non-A, non-B viral hepatitis genome, Science, 244, pp. 359-362, (1989)
  • [2] Kuo G., Choo Q.L., Alter H.J., Et al., An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis, Science, 244, pp. 362-364, (1989)
  • [3] Esteban J.I., Gonzalez A., Hernandez J.M., Et al., Evaluation of antibodies to hepatitis C virus in a study of posttransfusion associated hepatitis, N Engl J Med, 323, pp. 1107-1112, (1990)
  • [4] Kiyosawa K., Furuta S., Review of hepatitis C in Japan, J Gastroenterol Hepatol, 6, pp. 383-391, (1991)
  • [5] Esteban R., Esteban J.I., Lopez-Taravera J.C., Et al., Epidemiology of hepatitis C virus infection, Viral Hepatitis and Liver Disease, pp. 413-415, (1991)
  • [6] Nakatsuji Y., Matsumoto A., Tanaka E., Et al., Detection of chronic hepatitis C virus infection by four diagnostic systems: First-generation and second generation enzyme-linked immunosorbent assay, second-generation recombinant immunoblot assay and nested polymerase chin reaction analysis, Hepatology, 16, pp. 300-305, (1992)
  • [7] Watanabe J., Minegishi K., Mitsumori T., Et al., Prevalence of anti-HCV antibody in blood donors in the Tokyo area, Vox Sang, 59, pp. 86-88, (1990)
  • [8] Effect of screening for hepatitis C virus antibody ans hepatitis B virus core antibody on incidence of post-transfusion hepatitis, Lancet, 338, pp. 1040-1041, (1991)
  • [9] Koziol D.E., Holland P.V., Ailing D.W., Et al., Antibody to hepatitis B core antigen as a paradoxical marker for non-A, non-B hepatitis agents in donated blood, Ann Intern Med, 104, pp. 488-495, (1986)