INHIBITION OF THIAMINE TRANSPORT IN SACCHAROMYCES-CEREVISIAE BY THIAMINE DISULFIDES

被引:13
作者
IWASHIMA, A [1 ]
WAKABAYASHI, Y [1 ]
NOSE, Y [1 ]
机构
[1] KYOTO PREFECTURAL UNIV MED, DEPT BIOCHEM, KYOTO 602, JAPAN
关键词
D O I
10.1128/JB.131.3.1013-1015.1977
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Thiamine disulfide and O-benzoyl thiamine disulfide, which are thiolform derivatives of thiamine, strongly inhibited thiamine transport in S. cerevisiae. The inhibition apparently was due to a high affinity of the analogs for yeast cell membranes, in which thiamine transport component(s) may be integrated.
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页码:1013 / 1015
页数:3
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